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dNTP metabolism links mechanical cues and YAP/TAZ to cell growth and oncogene‐induced senescence
YAP/TAZ, downstream transducers of the Hippo pathway, are powerful regulators of cancer growth. How these factors control proliferation remains poorly defined. Here, we found that YAP/TAZ directly regulate expression of key enzymes involved in deoxynucleotide biosynthesis and maintain dNTP precursor...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983219/ https://ncbi.nlm.nih.gov/pubmed/29650681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797780 |
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