Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

Targeting MAIT cells holds promise for the treatment of different diseases and infections. We previously showed that treatment of Mycobacterium tuberculosis infected mice with 5-OP-RU, a major antigen for MAIT cells, expands MAIT cells and enhances bacterial control. Here we treated M. tuberculosis...

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Detaylı Bibliyografya
Yayımlandı:Mucosal Immunol
Asıl Yazarlar: Sakai, Shunsuke, Lora, Nickiana E., Kauffman, Keith D., Dorosky, Danielle E., Oh, Sangmi, Namasivayam, Sivaranjani, Gomez, Felipe, Fleegle, Joel D., Arlehamn, Cecilia S. Lindestam, Sette, Alessandro, Sher, Alan, Freeman, Gordon J., Via, Laura E., Barry III, Clifton E., Barber, Daniel L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group US 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217205/
https://ncbi.nlm.nih.gov/pubmed/34158594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-021-00425-3
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