Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

Targeting MAIT cells holds promise for the treatment of different diseases and infections. We previously showed that treatment of Mycobacterium tuberculosis infected mice with 5-OP-RU, a major antigen for MAIT cells, expands MAIT cells and enhances bacterial control. Here we treated M. tuberculosis...

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Bibliografiset tiedot
Julkaisussa:Mucosal Immunol
Päätekijät: Sakai, Shunsuke, Lora, Nickiana E., Kauffman, Keith D., Dorosky, Danielle E., Oh, Sangmi, Namasivayam, Sivaranjani, Gomez, Felipe, Fleegle, Joel D., Arlehamn, Cecilia S. Lindestam, Sette, Alessandro, Sher, Alan, Freeman, Gordon J., Via, Laura E., Barry III, Clifton E., Barber, Daniel L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group US 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217205/
https://ncbi.nlm.nih.gov/pubmed/34158594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-021-00425-3
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