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Meltos: multi-sample tumor phylogeny reconstruction for structural variants

MOTIVATION: We propose Meltos, a novel computational framework to address the challenging problem of building tumor phylogeny trees using somatic structural variants (SVs) among multiple samples. Meltos leverages the tumor phylogeny tree built on somatic single nucleotide variants (SNVs) to identify...

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Dades bibliogràfiques
Publicat a:Bioinformatics
Autors principals: Ricketts, Camir, Seidman, Daniel, Popic, Victoria, Hormozdiari, Fereydoun, Batzoglou, Serafim, Hajirasouliha, Iman
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215921/
https://ncbi.nlm.nih.gov/pubmed/31584621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz737
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