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Meltos: multi-sample tumor phylogeny reconstruction for structural variants
MOTIVATION: We propose Meltos, a novel computational framework to address the challenging problem of building tumor phylogeny trees using somatic structural variants (SVs) among multiple samples. Meltos leverages the tumor phylogeny tree built on somatic single nucleotide variants (SNVs) to identify...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8215921/ https://ncbi.nlm.nih.gov/pubmed/31584621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz737 |
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