PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data

Available computational methods for tumor phylogeny inference via single-cell sequencing (SCS) data typically aim to identify the most likely perfect phylogeny tree satisfying the infinite sites assumption (ISA). However, the limitations of SCS technologies including frequent allele dropout and vari...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Malikic, Salem, Mehrabadi, Farid Rashidi, Ciccolella, Simone, Rahman, Md. Khaledur, Ricketts, Camir, Haghshenas, Ehsan, Seidman, Daniel, Hach, Faraz, Hajirasouliha, Iman, Sahinalp, S. Cenk
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836735/
https://ncbi.nlm.nih.gov/pubmed/31628256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.234435.118
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