PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem

MOTIVATION: Recent advances in single-cell sequencing (SCS) offer an unprecedented insight into tumor emergence and evolution. Principled approaches to tumor phylogeny reconstruction via SCS data are typically based on general computational methods for solving an integer linear program, or a constra...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Sadeqi Azer, Erfan, Rashidi Mehrabadi, Farid, Malikić, Salem, Li, Xuan Cindy, Bartok, Osnat, Litchfield, Kevin, Levy, Ronen, Samuels, Yardena, Schäffer, Alejandro A, Gertz, E Michael, Day, Chi-Ping, Pérez-Guijarro, Eva, Marie, Kerrie, Lee, Maxwell P, Merlino, Glenn, Ergun, Funda, Sahinalp, S Cenk
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Genomic Variation Analysis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355310/
https://ncbi.nlm.nih.gov/pubmed/32657358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa464
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