PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem

MOTIVATION: Recent advances in single-cell sequencing (SCS) offer an unprecedented insight into tumor emergence and evolution. Principled approaches to tumor phylogeny reconstruction via SCS data are typically based on general computational methods for solving an integer linear program, or a constra...

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發表在:Bioinformatics
Main Authors: Sadeqi Azer, Erfan, Rashidi Mehrabadi, Farid, Malikić, Salem, Li, Xuan Cindy, Bartok, Osnat, Litchfield, Kevin, Levy, Ronen, Samuels, Yardena, Schäffer, Alejandro A, Gertz, E Michael, Day, Chi-Ping, Pérez-Guijarro, Eva, Marie, Kerrie, Lee, Maxwell P, Merlino, Glenn, Ergun, Funda, Sahinalp, S Cenk
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
主題:
Genomic Variation Analysis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355310/
https://ncbi.nlm.nih.gov/pubmed/32657358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa464
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