PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data

Available computational methods for tumor phylogeny inference via single-cell sequencing (SCS) data typically aim to identify the most likely perfect phylogeny tree satisfying the infinite sites assumption (ISA). However, the limitations of SCS technologies including frequent allele dropout and vari...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Malikic, Salem, Mehrabadi, Farid Rashidi, Ciccolella, Simone, Rahman, Md. Khaledur, Ricketts, Camir, Haghshenas, Ehsan, Seidman, Daniel, Hach, Faraz, Hajirasouliha, Iman, Sahinalp, S. Cenk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2019
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836735/
https://ncbi.nlm.nih.gov/pubmed/31628256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.234435.118
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