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Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions

BACKGROUND: Accumulation of alpha-synuclein (α-syn) is a main pathological hallmark of Parkinson’s and related diseases, which are collectively known as synucleinopathies. Growing evidence has supported that the same protein can induce remarkably distinct pathological progresses and disease phenotyp...

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Bibliografiske detaljer
Udgivet i:Transl Neurodegener
Main Authors: Liu, Di, Guo, Jian-Jun, Su, Ji-Hui, Svanbergsson, Alexander, Yuan, Lin, Haikal, Caroline, Li, Wen, Gouras, Gunnar, Li, Jia-Yi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215826/
https://ncbi.nlm.nih.gov/pubmed/34148543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-021-00242-5
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