Seeded propagation of α-synuclein aggregation in mouse brain using protein misfolding cyclic amplification

α-Synuclein (α-syn) protein aggregation is associated with several neurodegenerative disorders collectively referred to as synucleinopathies, including Parkinson’s disease. We used protein misfolding cyclic amplification (PMCA) to study α-syn aggregation in brain homogenates of wild-type or transgen...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Nicot, Simon, Verchère, Jérémy, Bélondrade, Maxime, Mayran, Charly, Bétemps, Dominique, Bougard, Daisy, Baron, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902716/
https://ncbi.nlm.nih.gov/pubmed/31370680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900354R
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