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Seeded propagation of α-synuclein aggregation in mouse brain using protein misfolding cyclic amplification

α-Synuclein (α-syn) protein aggregation is associated with several neurodegenerative disorders collectively referred to as synucleinopathies, including Parkinson’s disease. We used protein misfolding cyclic amplification (PMCA) to study α-syn aggregation in brain homogenates of wild-type or transgen...

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Vydáno v:FASEB J
Hlavní autoři: Nicot, Simon, Verchère, Jérémy, Bélondrade, Maxime, Mayran, Charly, Bétemps, Dominique, Bougard, Daisy, Baron, Thierry
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902716/
https://ncbi.nlm.nih.gov/pubmed/31370680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900354R
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