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Andrographis overcomes 5-fluorouracil-associated chemoresistance through inhibition of DKK1 in colorectal cancer

Colorectal cancer (CRC) ranks as the third leading cause of cancer-related deaths in the USA. 5-Fluorouracil (5FU)-based chemotherapeutic drug remains a mainstay of CRC treatment. Unfortunately, ~50–60% of patients eventually develop resistance to 5FU, leading to poor survival outcomes. Our previous...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Zhao, Yinghui, Wang, Chuanxin, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215595/
https://ncbi.nlm.nih.gov/pubmed/33822896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgab027
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