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Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells

Multidrug resistance is a major hindrance in managing cancer. By performing a series of experiments in chemoresistant colorectal cancer cell lines, we demonstrate that oligomeric proanthocyanidins (OPCs) from grape seed extracts can sensitize both acquired (HCT116-FOr cells) and innately chemoresist...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Ravindranathan, Preethi, Pasham, Divya, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514448/
https://ncbi.nlm.nih.gov/pubmed/30596962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy184
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