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Brusatol overcomes chemoresistance through inhibition of protein translation
The NRF2 pathway activates a cell survival response when cells are exposed to xenobiotics or are under oxidative stress. Therapeutic activation of NRF2 can also be used prior to insult as a means of disease prevention. However, prolonged expression of NRF2 has been shown to protect cancer cells by i...
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| Publicado no: | Mol Carcinog |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5404829/ https://ncbi.nlm.nih.gov/pubmed/28019675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22609 |
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