GSK-3 inhibition overcomes chemoresistance in human breast cancer

Glycogen Synthase Kinase-3β (GSK-3β), a serine/threonine protein kinase, is an emerging therapeutic target in the treatment of human breast cancer. In this study, we demonstrate that the pharmacological inhibition of GSK-3 by two novel small molecule GSK-3 inhibitors, 9-ING-41 and 9-ING-87, reduced...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancer Lett
Main Authors: Ugolkov, Andrey, Gaisina, Irina, Zhang, Jin-San, Billadeau, Daniel D., White, Kevin, Kozikowski, Alan, Jain, Sarika, Cristofanilli, Massimo, Giles, Francis, O’Halloran, Thomas, Cryns, Vincent L., Mazar, Andrew P.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786372/
https://ncbi.nlm.nih.gov/pubmed/27424289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.07.006
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker