Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a target for the treatment of cancer

Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, is a complex regulator of numerous cellular functions. GSK-3β is a unique kinase which is constitutively active in resting and non-stimulated cells. GSK-3β has been implicated in a wide range of diseases including neurodegenera...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Walz, Amy, Ugolkov, Andrey, Chandra, Sunandana, Kozikowski, Alan, Carneiro, Benedito A., O’Halloran, Thomas V, Giles, Francis J., Billadeau, Daniel D., Mazar, Andrew P.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392367/
https://ncbi.nlm.nih.gov/pubmed/28053024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2240
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