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Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity
The histone deacetylases (HDACs) occur in 11 different isoforms, and these enzymes regulate the activity of a large number of proteins involved in cancer initiation and progression. The discovery of isoform selective HDAC inhibitors (HDACIs) is desirable, as it is likely that such compounds would av...
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| Publicado no: | ChemMedChem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4818591/ https://ncbi.nlm.nih.gov/pubmed/26592932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500456 |
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