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Overcoming Chemoresistance of Pediatric Ependymoma by Inhibition of STAT3 Signaling
The long-term clinical outcome of pediatric intracranial epepdymoma is poor with a high rate of recurrence. One of the main reasons for this poor outcome is the tumor’s inherent resistance to chemotherapy. Signal transducer and activator of transcription 3 (STAT3) is overactive in many human cancers...
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Publicado no: | Transl Oncol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Neoplasia Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631088/ https://ncbi.nlm.nih.gov/pubmed/26500028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2015.08.001 |
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