Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer

Resistance to cytotoxic chemotherapy is a major cause of mortality in colorectal cancer (CRC) patients. Chemoresistance has been linked primarily to a subset of cancer cells undergoing epithelial–mesenchymal transition (EMT). Curcumin, a botanical with antitumorigenic properties, has been shown to e...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Toden, Shusuke, Okugawa, Yoshinaga, Jascur, Thomas, Wodarz, Dominik, Komarova, Natalia L., Buhrmann, Constanze, Shakibaei, Mehdi, Boland, C. Richard, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400529/
https://ncbi.nlm.nih.gov/pubmed/25653233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv006
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