Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer

BACKGROUND: To overcome the limitations of animal-based experiments, 3D culture models mimicking the tumor microenvironment in vivo are gaining attention. Herein, we investigated an alginate-based 3D scaffold for screening of 5-fluorouracil (5-FU) or/and curcumin on malignancy of colorectal cancer c...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Shakibaei, Mehdi, Kraehe, Patricia, Popper, Bastian, Shayan, Parviz, Goel, Ajay, Buhrmann, Constanze
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406109/
https://ncbi.nlm.nih.gov/pubmed/25884903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1291-0
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