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Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer
Resistance to cytotoxic chemotherapy is a major cause of mortality in colorectal cancer (CRC) patients. Chemoresistance has been linked primarily to a subset of cancer cells undergoing epithelial–mesenchymal transition (EMT). Curcumin, a botanical with antitumorigenic properties, has been shown to e...
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| Veröffentlicht in: | Carcinogenesis |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400529/ https://ncbi.nlm.nih.gov/pubmed/25653233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv006 |
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