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Targeting Tumor Cell Senescence and Polyploidy as Potential Therapeutic Strategies
Senescence is a unique state of growth arrest that develops in response to a plethora of cellular stresses, including replicative exhaustion, oxidative injury, and genotoxic insults. Senescence has been implicated in the pathogenesis of multiple aging-related pathologies, including cancer. In cancer...
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| Опубликовано в: : | Semin Cancer Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2022
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8214633/ https://ncbi.nlm.nih.gov/pubmed/33358748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2020.12.010 |
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