Therapy-Induced Senescence: An “Old” Friend Becomes the Enemy

For the past two decades, cellular senescence has been recognized as a central component of the tumor cell response to chemotherapy and radiation. Traditionally, this form of senescence, termed Therapy-Induced Senescence (TIS), was linked to extensive nuclear damage precipitated by classical genotox...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Saleh, Tareq, Bloukh, Sarah, Carpenter, Valerie J., Alwohoush, Enas, Bakeer, Jomana, Darwish, Sarah, Azab, Belal, Gewirtz, David A.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226427/
https://ncbi.nlm.nih.gov/pubmed/32235364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040822
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