Biliary excretion of excess iron in mice requires hepatocyte iron import by Slc39a14

Iron is essential for erythropoiesis and other biological processes, but is toxic in excess. Dietary absorption of iron is a highly regulated process and is a major determinant of body iron levels. Iron excretion, however, is considered a passive, unregulated process, and the underlying pathways are...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Prajapati, Milankumar, Conboy, Heather L., Hojyo, Shintaro, Fukada, Toshiyuki, Budnik, Bogdan, Bartnikas, Thomas B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214222/
https://ncbi.nlm.nih.gov/pubmed/34051234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100835
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