SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice

Solute carrier family 39, member 14 (SLC39A14) is a transmembrane transporter that can mediate the cellular uptake of zinc, iron, and manganese (Mn). Studies of Slc39a14 knockout (Slc39a14(−/−)) mice have documented that SLC39A14 is required for systemic growth, hepatic zinc uptake during inflammati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jenkitkasemwong, Supak, Akinyode, Adenike, Paulus, Elizabeth, Weiskirchen, Ralf, Hojyo, Shintaro, Fukada, Toshiyuki, Giraldo, Genesys, Schrier, Jessica, Garcia, Armin, Janus, Christopher, Giasson, Benoit, Knutson, Mitchell D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828629/
https://ncbi.nlm.nih.gov/pubmed/29437953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720739115
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados