SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

Nearly all forms of hereditary hemochromatosis are characterized by pathological iron accumulation in the liver, pancreas, and heart. These tissues preferentially load iron because they take up non-transferrin-bound iron (NTBI), which appears in the plasma during iron overload. Yet, how tissues take...

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Détails bibliographiques
Publié dans:Cell Metab
Auteurs principaux: Jenkitkasemwong, Supak, Wang, Chia-Yu, Coffey, Richard, Zhang, Wei, Chan, Alan, Biel, Thomas, Kim, Jae-Sung, Hojyo, Shintaro, Fukada, Toshiyuki, Knutson, Mitchell D.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497937/
https://ncbi.nlm.nih.gov/pubmed/26028554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.05.002
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