SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

Nearly all forms of hereditary hemochromatosis are characterized by pathological iron accumulation in the liver, pancreas, and heart. These tissues preferentially load iron because they take up non-transferrin-bound iron (NTBI), which appears in the plasma during iron overload. Yet, how tissues take...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Jenkitkasemwong, Supak, Wang, Chia-Yu, Coffey, Richard, Zhang, Wei, Chan, Alan, Biel, Thomas, Kim, Jae-Sung, Hojyo, Shintaro, Fukada, Toshiyuki, Knutson, Mitchell D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497937/
https://ncbi.nlm.nih.gov/pubmed/26028554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.05.002
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