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Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

Chiral tertiary boronic esters are important precursors to bioactive compounds and versatile synthetic intermediates to molecules containing quaternary stereocenters. The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Gao, Tao-Tao, Lu, Hou-Xiang, Gao, Peng-Chao, Li, Bi-Jie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213697/
https://ncbi.nlm.nih.gov/pubmed/34145273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24012-z
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