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Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

Chiral tertiary boronic esters are important precursors to bioactive compounds and versatile synthetic intermediates to molecules containing quaternary stereocenters. The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the a...

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Publicat a:Nat Commun
Autors principals: Gao, Tao-Tao, Lu, Hou-Xiang, Gao, Peng-Chao, Li, Bi-Jie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213697/
https://ncbi.nlm.nih.gov/pubmed/34145273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24012-z
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