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Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages
The HIV-1 accessory proteins Vif, Vpu, and Nef can promote infection by overcoming the inhibitory effects of the host cell restriction factors APOBEC3G, Tetherin, and SERINC5, respectively. However, how the HIV-1 accessory protein Vpr enhances infection in macrophages but not in CD4(+) T cells remai...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8211709/ https://ncbi.nlm.nih.gov/pubmed/34140527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24087-8 |
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