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HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells

Lentiviruses, including HIV-1, possess the ability to enter the nucleus through nuclear pore complexes and can infect interphase cells, including those actively replicating chromosomal DNA. Viral accessory proteins hijack host cell E3 enzymes to antagonize intrinsic defenses, and thereby provide a m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yan, Junpeng, Shun, Ming-Chieh, Zhang, Yi, Hao, Caili, Skowronski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511057/
https://ncbi.nlm.nih.gov/pubmed/31019079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818401116
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