HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins

HIV replication in nondividing host cells occurs in the presence of high concentrations of noncanonical dUTP, apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) cytidine deaminases, and SAMHD1 (a cell cycle-regulated dNTP triphosphohydrolase) dNTPase, which maintains low c...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hrecka, Kasia, Hao, Caili, Shun, Ming-Chieh, Kaur, Sarabpreet, Swanson, Selene K., Florens, Laurence, Washburn, Michael P., Skowronski, Jacek
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941427/
https://ncbi.nlm.nih.gov/pubmed/27335459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605023113
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