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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
Macrophages and dendritic cells play key roles in viral infections, providing virus reservoirs that frequently resist anti-viral therapies and linking innate virus detection to anti-viral adaptive immune responses(1,2). HIV-1 fails to transduce dendritic cells and has a reduced ability to transduce...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3179858/ https://ncbi.nlm.nih.gov/pubmed/21720370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10195 |
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