Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages

HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis. Vpr counteracts a previously unknown macrophage-specific restriction factor that targets and reduces the...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Lubow, Jay, Virgilio, Maria C, Merlino, Madeline, Collins, David R, Mashiba, Michael, Peterson, Brian G, Lukic, Zana, Painter, Mark M, Gomez-Rivera, Francisco, Terry, Valeri, Zimmerman, Gretchen, Collins, Kathleen L
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Immunology and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7051176/
https://ncbi.nlm.nih.gov/pubmed/32119644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51035
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