mTORC2 Controls PKC and Akt by Phosphorylating a Conserved TOR-Interaction Motif

The kinase complex mTORC2 is widely accepted as controlling phosphorylation of the hydrophobic motif, a key regulatory switch in the C-terminal tail of protein kinase C (PKC), Akt, and other AGC kinases. Yet the biochemical mechanism by which it controls this site and whether mTOR is the direct hydr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Baffi, Timothy R., Lordén, Gema, Wozniak, Jacob M., Feichtner, Andreas, Yeung, Wayland, Kornev, Alexandr P., King, Charles C., Del Rio, Jason C., Limaye, Ameya J., Bogomolovas, Julius, Gould, Christine M., Chen, Ju, Kennedy, Eileen J., Kannan, Natarajan, Gonzalez, David J., Stefan, Eduard, Taylor, Susan S., Newton, Alexandra C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8208635/
https://ncbi.nlm.nih.gov/pubmed/33850054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abe4509
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados