CRISPR-CasΦ from huge phages is a hypercompact genome editor

CRISPR-Cas systems are found widely in prokaryotes where they provide adaptive immunity against virus infection and plasmid transformation. We describe a minimal functional CRISPR-Cas system, comprising a single ~70 kilodalton protein, CasΦ, and a CRISPR array, encoded exclusively in the genomes of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Pausch, Patrick, Al-Shayeb, Basem, Bisom-Rapp, Ezra, Tsuchida, Connor A., Li, Zheng, Cress, Brady F., Knott, Gavin J., Jacobsen, Steven E., Banfield, Jillian F., Doudna, Jennifer A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207990/
https://ncbi.nlm.nih.gov/pubmed/32675376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb1400
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