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CRISPR-CasΦ from huge phages is a hypercompact genome editor
CRISPR-Cas systems are found widely in prokaryotes where they provide adaptive immunity against virus infection and plasmid transformation. We describe a minimal functional CRISPR-Cas system, comprising a single ~70 kilodalton protein, CasΦ, and a CRISPR array, encoded exclusively in the genomes of...
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| Publicado en: | Science |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8207990/ https://ncbi.nlm.nih.gov/pubmed/32675376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb1400 |
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