CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus

Many bacteria rely on CRISPR-Cas systems to provide adaptive immunity against phages, predation by which can shape the ecology and functioning of microbial communities. To characterize the impact of CRISPR immunization on phage genome evolution, we performed long-term bacterium-phage (Streptococcus...

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Bibliographic Details
Published in:mBio
Main Authors: Paez-Espino, David, Sharon, Itai, Morovic, Wesley, Stahl, Buffy, Thomas, Brian C., Barrangou, Rodolphe, Banfield, Jillian F.
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453577/
https://ncbi.nlm.nih.gov/pubmed/25900652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00262-15
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