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Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex
CRISPR-Cas systems provide adaptive immunity in bacteria and archaea, beginning with integration of foreign sequences into the host CRISPR genomic locus and followed by transcription and maturation of CRISPR RNAs (crRNAs). In some CRISPR systems, a reverse transcriptase (RT) fusion to the Cas1 integ...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8102632/ https://ncbi.nlm.nih.gov/pubmed/33958590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22900-y |
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