Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay

BACKGROUND: Clinical outcomes in high-grade glioma (HGG) have remained relatively unchanged over the last 3 decades with only modest increases in overall survival. Despite the validation of biomarkers to classify treatment response, most newly diagnosed (ND) patients receive the same treatment regim...

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Bibliografische gegevens
Gepubliceerd in:Neurooncol Adv
Hoofdauteurs: Shuford, Stephen, Lipinski, Lindsay, Abad, Ajay, Smith, Ashley M, Rayner, Melissa, O’Donnell, Lauren, Stuart, Jeremy, Mechtler, Laszlo L, Fabiano, Andrew J, Edenfield, Jeff, Kanos, Charles, Gardner, Stephen, Hodge, Philip, Lynn, Michael, Butowski, Nicholas A, Han, Seunggu J, Redjal, Navid, Crosswell, Howland E, Vibat, Cecile Rose T, Holmes, Lillia, Gevaert, Matthew, Fenstermaker, Robert A, DesRochers, Teresa M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
Onderwerpen:
Basic and Translational Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207705/
https://ncbi.nlm.nih.gov/pubmed/34142085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab065
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