Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay

BACKGROUND: Clinical outcomes in high-grade glioma (HGG) have remained relatively unchanged over the last 3 decades with only modest increases in overall survival. Despite the validation of biomarkers to classify treatment response, most newly diagnosed (ND) patients receive the same treatment regim...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Shuford, Stephen, Lipinski, Lindsay, Abad, Ajay, Smith, Ashley M, Rayner, Melissa, O’Donnell, Lauren, Stuart, Jeremy, Mechtler, Laszlo L, Fabiano, Andrew J, Edenfield, Jeff, Kanos, Charles, Gardner, Stephen, Hodge, Philip, Lynn, Michael, Butowski, Nicholas A, Han, Seunggu J, Redjal, Navid, Crosswell, Howland E, Vibat, Cecile Rose T, Holmes, Lillia, Gevaert, Matthew, Fenstermaker, Robert A, DesRochers, Teresa M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207705/
https://ncbi.nlm.nih.gov/pubmed/34142085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab065
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