Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay

BACKGROUND: Clinical outcomes in high-grade glioma (HGG) have remained relatively unchanged over the last 3 decades with only modest increases in overall survival. Despite the validation of biomarkers to classify treatment response, most newly diagnosed (ND) patients receive the same treatment regim...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Shuford, Stephen, Lipinski, Lindsay, Abad, Ajay, Smith, Ashley M, Rayner, Melissa, O’Donnell, Lauren, Stuart, Jeremy, Mechtler, Laszlo L, Fabiano, Andrew J, Edenfield, Jeff, Kanos, Charles, Gardner, Stephen, Hodge, Philip, Lynn, Michael, Butowski, Nicholas A, Han, Seunggu J, Redjal, Navid, Crosswell, Howland E, Vibat, Cecile Rose T, Holmes, Lillia, Gevaert, Matthew, Fenstermaker, Robert A, DesRochers, Teresa M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8207705/
https://ncbi.nlm.nih.gov/pubmed/34142085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab065
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