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Diverse contributions of avidity to the broad neutralization of Dengue virus by antibodies targeting the E dimer epitope

Antibodies (Abs) recognizing the Dengue virus (DENV) E dimer epitope (EDE) that potently neutralize all DENV serotypes are promising templates for vaccine design. As an important feature for some Abs is their bivalency, we sought to define the role avidity plays in neutralization by EDE Abs. We comp...

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Bibliografski detalji
Izdano u:Virology
Glavni autori: Remmel, Jennifer L, Frei, Julia C, Butler, Savannah E, Lai, Jonathan R, Ackerman, Margaret E
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205970/
https://ncbi.nlm.nih.gov/pubmed/33819753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2021.03.013
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