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Diverse contributions of avidity to the broad neutralization of Dengue virus by antibodies targeting the E dimer epitope

Antibodies (Abs) recognizing the Dengue virus (DENV) E dimer epitope (EDE) that potently neutralize all DENV serotypes are promising templates for vaccine design. As an important feature for some Abs is their bivalency, we sought to define the role avidity plays in neutralization by EDE Abs. We comp...

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Detaylı Bibliyografya
Yayımlandı:Virology
Asıl Yazarlar: Remmel, Jennifer L, Frei, Julia C, Butler, Savannah E, Lai, Jonathan R, Ackerman, Margaret E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205970/
https://ncbi.nlm.nih.gov/pubmed/33819753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2021.03.013
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