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Diverse contributions of avidity to the broad neutralization of Dengue virus by antibodies targeting the E dimer epitope

Antibodies (Abs) recognizing the Dengue virus (DENV) E dimer epitope (EDE) that potently neutralize all DENV serotypes are promising templates for vaccine design. As an important feature for some Abs is their bivalency, we sought to define the role avidity plays in neutralization by EDE Abs. We comp...

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Bibliografiska uppgifter
I publikationen:Virology
Huvudupphovsmän: Remmel, Jennifer L, Frei, Julia C, Butler, Savannah E, Lai, Jonathan R, Ackerman, Margaret E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205970/
https://ncbi.nlm.nih.gov/pubmed/33819753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2021.03.013
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