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Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore
Coupling of Atg8 to phosphatidylethanolamine is crucial for the expansion of the crescent-shaped phagophore during cargo engulfment. Atg21, a PtdIns3P-binding beta-propeller protein, scaffolds Atg8 and its E3-like complex Atg12–Atg5-Atg16 during lipidation. The crystal structure of Atg21, in complex...
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| 出版年: | Autophagy |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8205015/ https://ncbi.nlm.nih.gov/pubmed/32515645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1766332 |
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