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GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis

Perhaps the most complex step of macroautophagy is the formation of the double-membrane autophagosome. The majority of the autophagy-related (Atg) proteins are thought to participate in nucleation and expansion of the phagophore, and/or the completion of this compartment. Monitoring this part of the...

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Detalhes bibliográficos
Main Authors: Nair, Usha, Thumm, Michael, Klionsky, Daniel J., Krick, Roswitha
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327617/
https://ncbi.nlm.nih.gov/pubmed/22108003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.12.18424
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