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PI3P binding by Atg21 organises Atg8 lipidation
Autophagosome biogenesis requires two ubiquitin-like conjugation systems. One couples ubiquitin-like Atg8 to phosphatidylethanolamine, and the other couples ubiquitin-like Atg12 to Atg5. Atg12∽Atg5 then forms a heterodimer with Atg16. Membrane recruitment of the Atg12∽Atg5/Atg16 complex defines the...
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| Gepubliceerd in: | EMBO J |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BlackWell Publishing Ltd
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388602/ https://ncbi.nlm.nih.gov/pubmed/25691244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488957 |
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