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Autophagy is critical for cysteine metabolism in pancreatic cancer through regulation of SLC7A11

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer. The elevated macroautophagy/autophagy in these tumors supports growth, promotes immune evasion, and increases therapeutic resistance. Therefore, targeting autophagy is a therapeutic strategy that is being pursued to tre...

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Bibliographic Details
Published in:Autophagy
Main Authors: Mukhopadhyay, Subhadip, Kimmelman, Alec C.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204992/
https://ncbi.nlm.nih.gov/pubmed/33985415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1922984
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