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Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease
Mitochondrial dysfunction is behind several neurodegenerative diseases, including Alzheimer disease (AD). Accumulation of damaged mitochondria is already observed at the early stages of AD and has been linked to impaired mitophagy, but the mechanisms underlying this alteration are still not fully kn...
Guardat en:
| Publicat a: | Autophagy |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204952/ https://ncbi.nlm.nih.gov/pubmed/33945386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1920814 |
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