ArfGAP1 inhibits mTORC1 lysosomal localization and activation

The mammalian target of rapamycin complex 1 (mTORC1) integrates nutrients, growth factors, stress, and energy status to regulate cell growth and metabolism. Amino acids promote mTORC1 lysosomal localization and subsequent activation. However, the subcellular location or interacting proteins of mTORC...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Meng, Delong, Yang, Qianmei, Melick, Chase H, Park, Brenden C, Hsieh, Ting‐Sung, Curukovic, Adna, Jeong, Mi‐Hyeon, Zhang, Junmei, James, Nicholas G, Jewell, Jenna L
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204869/
https://ncbi.nlm.nih.gov/pubmed/33988249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106412
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