ArfGAP1 inhibits mTORC1 lysosomal localization and activation

The mammalian target of rapamycin complex 1 (mTORC1) integrates nutrients, growth factors, stress, and energy status to regulate cell growth and metabolism. Amino acids promote mTORC1 lysosomal localization and subsequent activation. However, the subcellular location or interacting proteins of mTORC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Meng, Delong, Yang, Qianmei, Melick, Chase H, Park, Brenden C, Hsieh, Ting‐Sung, Curukovic, Adna, Jeong, Mi‐Hyeon, Zhang, Junmei, James, Nicholas G, Jewell, Jenna L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204869/
https://ncbi.nlm.nih.gov/pubmed/33988249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106412
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